Khloé Kardashian has previously tried to shut down speculation that she used the weight-loss drugs to help her slim down.

But she and her sister Kim Kardashian, 42, were beset by fan speculation that they had been using a popular anti-diabetes drug when they posted photos of their newly chiseled abs on Monday.

Several fans and critics called out the famous sisters for supposedly using weight-loss substances, despite their denials and a lack of concrete evidence that they had used Semaglutide, which is also known by the brand names Ozempic, Wegovy and Rybelsus.

Some fans even went as far as to accuse the reality stars of shooting an ad for Ozempic due to their significant weight loss.

‘An Ozempic ad is what I see here,’ wrote one accusatory account in the comments to their Instagram posts.

Picture perfect: Kim Kardashian, 42, and her sister Khloé, 38, were beset by comments speculating that they had used popular anti-diabetes drugs to lose weight after they showcased their rock-solid abs on Instagram on Monday

My how they’ve changed: The stars both proudly showcased their much trimmer bodies

Before: Kim, who calls herself a ‘shapeshifter’, is pictured here in a candid snap in 2017. Khloe is pictured right in 2018

Another person joked, ‘Save some insulin for the people who actually need it,’ though the drugs that many fans speculated that they had been using are distinct from the insulin that many diabetic people require.

Others complained more generally about the sisters’ weight loss, insisting that they were ‘too slim.’

One particularly cruel comment appeared to be directed at Khloé: ‘Her hands look too thin eat something you look hungry.’

Another user joked that Khloé was ‘barely flexing,’ while Kim was ‘holding it in.’

Another user bemoaned the ‘money spent on those bodies.’

Other users complained more generally about Kim and Khloé’s recent weight loss, though Khloé’s physical transformation has been more gradual, and she has regularly highlighted her intense workouts for years.

‘What are yall trying to see who can show all their ribs the fastest???wtf,’ commented one person.

Others sounded nostalgic for the sisters’ curves of years past.

Pointing fingers: Some fans even went as far as to accuse the reality stars of shooting an ad for Ozempic due to their significant weight loss. The drug is one brand name of Semaglutide, which suppresses appetite and is intended for people with type 2 diabetes

Ouch: One particularly cruel comment appeared to be directed at Khloé: ‘Her hands look too thin eat something you look hungry,’ while another person joked that Khloé was ‘barely flexing’ while Kim was ‘holding it in’

 

Wasteful: Another user bemoaned the ‘money spent on those bodies’

Lashing out: Other users complained more generally about Kim and Khloé’s recent weight loss, though Khloé’s physical transformation has been more gradual, and she has regularly highlighted her intense workouts for years

Having a laugh: Although Khloé described herself and Kim as Calabasas girls in her caption, one user suggested ‘Ozempic girls’ might be more accurate

Harming others: While wealthy customers have flocked to get Ozempic prescriptions to lose weight, its popularity has led to shortages for people who have type 2 diabetes and actually need it

‘When are you guys gonna bring curvy back….asking for a friend,’ read one critical comment.

Although Khloé described herself and Kim as Calabasas girls in her caption, one user suggested ‘Ozempic girls’ might be more accurate.

Another person simply wrote, ‘Somebody please feed them 😬.’

Ozempic is manufactured by Danish pharmaceutical giant Novo Nordisk and costs around $900 per dose.

The injectable version can be used on the stomach, thigh or arm, and it quickly works to suppress a person’s appetite, which can be useful in allowing them to shed weight.

It is currently only approved by the FDA as a type 2 diabetes treatment, but many medical providers have begun prescribing it off label as a weight-loss drug recently, and it has skyrocketed in popularity among wealthy customers looking to slim down.

However, the rush of rich people looking to buy the drug has created shortages that harm diabetic people who most need it for their health.

Despite several of the negative comments, Kim and Khloé were still showered with plenty of praise for the stellar physiques.

The duo — who each recently shared photos of their combined broods — matched each other in gray and black versions of the same outfit.

Both were tantalizing as they flashed their ample and perky cleavage in plunging bra tops.

Social media: Kim and Khloe put on a sizzling display in their photos shared to Instagram on Monday. They wore looks designed to showcased their new abs

Picture perfect: The 42-year-old mogul and her younger sibling, 38, looked like dolls as they bared their enviable abs

Smokin’ hot: Both were tantalizing as they flashed their ample and perky cleavage in plunging bra tops

Kim wrote in the caption of her post, ‘Kiki & Koko,’ and added an infinity emoji.

The family members zeroed in on their sex appeal as they showed off their vixen-like qualities.

Kim’s low-slung skirt was set beautifully on her curvy hips, flattering her figure as it draped over her.

She played up the placement of the piece as she donned a glinting diamond chain around her belly.

Her maxi skirt featured a thigh-high slit that flashed her toned and tanned leg and showed off a sparkling anklet around her ankle.

Additionally, the billionaire businesswoman wore a diamond-encrusted ‘KIM’ nameplate necklace.

Transformation: Khloe proudly put her tiny waist on show in racy bikini snaps on Monday

The former Mrs. West wore her lustrous dark locks in a center part as she let the butt-length tresses tumble down her back and over her shoulder.

The superstar was typically gorgeous with her world-recognized visage made up to perfection.

She looked glowy with her eyebrows arched, eyes highlighted with fluffy lashes, and her cheeks blushed.

Meanwhile, Khloe contrasted her big sister as she went for a darker version of the ensemble.

The mom-of-two, who shares daughter True and a baby son with ex Tristan Thompson, wowed as she put her individual touch on the look.

The Good American co-founder looked like a pinup doll as she modeled her onyx skirt, which had a slightly higher waistband than Kim’s.

She put her taut abdomen front and center as she struck several poses with the second-born Kardashian.

Khloe accented her presentation with a pop of a classic bright red color via a matching manicure and pedicure.

Known for their distinct tastes in nails — Khloe rocked a long and sharp style while Kim went with a short, nude option.

The blonde bombshell wore dainty necklaces and stacked bangles on one wrist.

Her honey-hued hair was arranged into an intentionally messy mop of curls set at the top of her head.

Flirty and long loose pieces were left out in front, providing a frame for the rest of the look.

Hair stylist Chris Appleton, who made an appearance in two of the carousel photos, commented: ‘That’s HOT.’